February 2021

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Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder associated with the death of motor neurons. These are nerve cells that control the voluntary muscles, which are essential for movement.   As the condition progresses, the muscles weaken and waste away, resulting in a loss of muscle control. Although ALS can progress differently in each […]

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MND study provides exciting new focus for potential drug treatments

January 2021: Motor neurone disease treatments that boost energy in nerve cells could be developed thanks to new research. Researchers at the Euan MacDonald Centre for MND Research have recently published the findings of a research study that has provided a new focus for potential drug treatments for MND.   The research team created a

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A prospective harmonized multicenter DTI study of cerebral white matter degeneration in ALS

Abstract Objective To evaluate progressive white matter (WM) degeneration in amyotrophic lateral sclerosis (ALS).   Methods Sixty-six patients with ALS and 43 healthy controls were enrolled in a prospective, longitudinal, multicenter study in the Canadian ALS Neuroimaging Consortium (CALSNIC). Participants underwent a harmonized neuroimaging protocol across 4 centers that included diffusion tensor imaging (DTI) for

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